cid 6aca5d54f601af564deefb7bee7b06d205093227a46a8b2a15772d71d1270194 · original · via openalex
Title: Optimization of Continuous Countercurrent Extraction Process of Egui Yangxue Prescription Authors: Hui Chen Venue: Zhongguo shiyan fangjixue zazhi Year: 2012 Canonical: openalex:https://openalex.org/W2358642588 URL: https://openalex.org/W2358642588 Collector: openalex OA: false ABSTRACT Objective:To optimize continuous countercurrent extraction process of Egui Yangxue prescription.Method: With the content of ferulic acid and the amount of extract as indexes,the content of ferulic acid was determined by HPLC,optimum continuous countercurrent extraction process of Egui Yangxue prescription was determined by multi-index comprehensive evaluation method and orthogonal design.Factors of extraction time,solid-liquid ratio,the concentration of ethanol and extraction temperature were investigated.Result: Optimum extraction process was:solid-liquid ratio of 1∶16(equivalent to each level liquid ratio of 1∶4),extracted 20 min with 60% ethanol under extraction temperature of 40 ℃.Conclusion: This optimized extraction process was stable and reliable,and it could provide scientific basis for relative research of Egui Yangxue prescription.